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· Shipment Port: Shanghai, Tianjin，Guangzhou, Qingdao
· MOQ:100,000boxes
· Payment Terms: T/T, L/C
Composition:
Each 5 ml contains: Cefixime (as Trihydrate) 100 mg after reconstituted with water.
Indications:
Cefixime Suspension (cefixime (as Trihydrate)) is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: Uncomplicated Urinary Tract Infections.
Otitis Media.
Pharyngitis and Tonsillitis.
Acute Bronchitis and Acute Exacerbations of Chronic Bronchitis.
Contra-indications:
Cefixime Suspension is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Treatment with broad-spectrum antibiotics, including Cefixime Suspension, alters the normal flora of the colon and may permit overgrowth of clostridia. Pseudomembranous colitis has been reported with the use of Cefixime Suspension and other broad-spectrum antibiotics (including macrolides, semisynthetic penicillins. And cephalosporins).
Side Effects:
The following adverse reactions have been reported following the use of Cefixime Suspension. Incidence rates were less than 1 in 50 (less than 2%). Diarrhea, loose stools, abdominal pain, dyspepsia, nausea, and vomiting.
Transient elevations in SGPT, SGOT, and alkaline phosphatase.
Renal: Transient elevations in BUN or creatinine.
Central Nervous System: Headaches or dizziness.
Drugs and Interaction:
Carbamazepine: Elevated carbamazepine levels have been reported.
DRUG/LABORATORY TEST INTERACTIONS:
A false-poditive reaction for ketones in the urine may occur with tests using nitroprusside. The administration of Cefixime Suspension may result in a false-positive reaction for glucose in the urine using Benedict’ solution, or Fehling’ solution.
Usage in Pregnancy
Pregnancy Category B. Reproduction studies have been performed in mice and rats at doses up to 400 times the human dose and have revealed no evidence of harm to the fetus due to Cefixime Suspension. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed.
Nursing Mothers:
It is not known whether Cefixime Suspension is excreted in human milk. Consideration should be given to discontinuing nursing temporarily during treatment with this drug.
Pediatric Use:
Safety and effectiveness of Cefixime Suspension in children aged less than 6 months old have not been established.
Warnings:
Before therapy with Cefixime Suspension is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporins, penicillins. If an allergic reaction to Cefixime Suspension occurs, discontinue the use of drug, and appropriate measures should be take.
The dose of Cefixime Suspension should be adjusted in patients with renal impairment as well as those undergoing continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD).
Overdose:
Gastric lavage may be indicated, otherwise, no specific antidote exists. Cefixime is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis.
Dosage and administration:
Oral suspension.
Adults: The recommended dose of Cefixime Suspension is 400 mg daily. This may be given as a 400 mg tablet daily or as 200 mg tablet every 12 hours.
For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is recommended.
Children: The recommended dose is 8 mg/kg/day of the suspension. This may be administered as a single daily dose or may be given in two divided doses, as 4 mg/kg every 12 hours.
Storage directions:
Store in a dry place below 25℃.
Keep out of reach of children.
Shelf validity:
3 years.
