News.pharmnet.com.cn 2021-11-25 Kina Pūnaewele Nūhou
Ma ka lā 23 o Nowemapa, Chongqing GAOJIN Biotechnology Co., Ltd. (i kapa ʻia ʻo "GAOJIN biotechnology") o ka waihona ʻoihana olaola aupuni o Chongqing kiʻekiʻe ʻenehana Zone hoʻolaha ʻia ma muli o ka non radioactive isotope boron-10, ua hoʻomohala maikaʻi ia i ka. ʻO ka lāʻau boron BPA mua no nā maʻi maʻi maʻi e like me ka melanoma, ka lolo a me ka glioma, i mālama ʻia e BNCT, ʻo ia hoʻi ka boron neutron capture therapy Hiki i nā minuke 30 ke ho'ōla i nā ʻano maʻi maʻi maʻi kūikawā.
ʻO BNCT kekahi o nā ala lapaʻau maʻi maʻi ʻoi loa ma ka honua.Hoʻopau ʻo ia i nā maʻi maʻi maʻi ma o ka hopena nuklea atomic i loko o nā cell tumor.ʻO kāna kumu lapaʻau: e hoʻokomo mua i ka boron non-toxic a me ka pōʻino ʻole i loko o ka lāʻau i loko o ka mea maʻi.Ma hope o ke komo ʻana o ka lāʻau lapaʻau i ke kino o ke kanaka, hoʻopaʻa koke ʻo ia a hōʻiliʻili i loko o nā keʻena maʻi kanesa.I kēia manawa, hoʻohana ʻia kahi ray neutron me ka liʻiliʻi o ka pōʻino i ke kino o ke kanaka no ka irradiation.Ma hope o ka hui ʻana o ka neutron me ka boron i ke komo ʻana i loko o nā keʻena maʻi maʻi, ua hoʻokumu ʻia kahi "nuclear reaction" ikaika, e hoʻokuʻu ana i kahi kukui ion kaumaha nui loa.He pōkole loa ka laulā o ka hihi, hiki iā ia ke pepehi wale i nā pūnana maʻi maʻi me ka ʻole e hōʻino i nā ʻiʻo a puni.ʻO kēia ʻenehana radiotherapy i koho ʻia e pepehi wale i nā maʻi kanesa me ka ʻole e hōʻino i nā ʻiʻo maʻamau i kapa ʻia ʻo boron neutron capture therapy.
I kēia manawa, ua hoʻopau ka BPA boron lāʻau me GAOJIN biological code o "gjb01" i ka noiʻi lāʻau lapaʻau o API a me ka hoʻomākaukau ʻana, a ua hoʻopau i ka hōʻoia ʻana i ke kaʻina hana hoʻomākaukau ana.Ma hope, hiki ke hoʻohana ʻia i loko o nā hui R&D o BNCT neutron therapy device ma Kina e hana i ka noiʻi kūpono, hoʻokolohua a me ka noi lapaʻau.He mea pono e hoʻomaopopo i ka hana hoʻokele he loulou kūpono no ka hoʻololi ʻana i nā hana ʻepekema a me ka ʻenehana i nā ikaika huahua, a ʻo ka kūleʻa a i ʻole ka hemahema o ka ʻoihana hoʻokō e hilinaʻi nui ʻia i ka kūleʻa a i ʻole ka hāʻule ʻole o ka hana hoʻokele.
I Malaki 2020, ua ʻae ʻia ʻo steboronine, ka mea mua BNCT o ka honua a me ka lāʻau boron mua o ka honua, no ke kūʻai aku ʻana ma Iapana no ka maʻi maʻi poʻo a me ka ʻāʻī hou ʻole.Eia kekahi, ua lawe ʻia nā haneli o nā hoʻokolohua lapaʻau i loko o ka lolo lolo, melanoma malignant, ka maʻi ʻaʻai māmā, ka mesothelioma pleural, ka maʻi ʻaʻai a me ka maʻi maʻi umauma, a ua loaʻa nā ʻikepili hoʻōla maikaʻi.
Ua ʻōlelo ʻo Cai Shaohui, ka hope luna nui a me ke alakaʻi o ka papahana o GAOJIN biology, ʻo ka papa kuhikuhi holoʻokoʻa o "gjb01" ua kūlike loa me nā lāʻau steboronine i helu ʻia ma Iapana, a ʻoi aku ka kiʻekiʻe o ke kumukūʻai.Manaʻo ʻia e hoʻohana ʻia i ka lāʻau lapaʻau i ka makahiki 2023 a ua manaʻo ʻia e lilo ʻo ia i papa inoa mua o ka BNCT anti-cancer boron drug ma Kina.
Ua ʻōlelo ʻo Cai Shaohui, "ʻaʻole kānalua ke ʻano holomua o ka mālama ʻana iā BNCT.ʻO ke kumu ka lāʻau boron.ʻO ka pahuhopu o ka biology Jin kiʻekiʻe ʻo ia ka hoʻokō ʻana i ka mālama ʻana o Kina BNCT i ka pae kiʻekiʻe o ka honua.Hiki ke hoʻomalu maikaʻi ʻia ke kumukūʻai o ka mālama ʻana ma kahi o 100 tausani yuan, i hiki i nā poʻe maʻi me ke kanesa ke loaʻa i ka lāʻau lapaʻau a loaʻa ke kālā e hoʻōla ai.
"Hiki ke kapa ʻia ka lāʻau BNCT ʻo ka 'momi ma ka lei aliʻi' o ka mālama ʻana i ka maʻi maʻi maʻi no ka haʻahaʻa haʻahaʻa, ka pōkole o ka lāʻau lapaʻau (30-60 mau minuke i kēlā me kēia manawa, hiki ke hoʻōla ʻia ka lāʻau wikiwiki loa i hoʻokahi a ʻelua wale nō), nā hōʻailona ākea a haʻahaʻa. nā hopena ʻaoʻao."Ua ʻōlelo ʻo Wang Jian, Luna Nui o GAOJIN biology, ʻo ke kī koʻikoʻi ke kaʻina hana a me ka hoʻomākaukau ʻana o nā lāʻau boron, ʻo ia ka mea e hoʻoholo ai inā hiki i ka lāʻau lapaʻau ke mālama pono i nā ʻano o ka maʻi kanesa.
Ka manawa hoʻouna: Nov-25-2021