Ua ʻike ka haʻawina i ka amoxicillin waha palekana a maikaʻi hoʻi no nā wahine hāpai maʻi i ka penicillin

Kanada: Ua hiki i nā wāhine hāpai, me ka mōʻaukala o ka maʻi maʻi penicillin ke hoʻopau pono i ka waha pololeiamoxicillinnā pilikia me ka ʻole o ka hoʻāʻo ʻana i ka ʻili ma mua, wahi a kahi ʻatikala i paʻi ʻia maʻO ka Journal of Allergy and Clinical Immunology: I ka hoʻomaʻamaʻa.

I loko o nā kānaka maʻi like ʻole, ua ʻike ʻia ka palekana a me ka kūleʻa o ka penicillin allergy de-labelling i nā poʻe haʻahaʻa haʻahaʻa.Hōʻike ka hoʻāʻo ʻana ma mua o 90% o ka poʻe ʻaʻole maʻi maʻi ma kahi mua.ʻOiai ʻaʻole hoʻonui ka hāpai ʻana i ka maʻi allergy penicillin, haʻalele pinepine ʻia nā wahine hāpai mai ka hapa nui o ka noiʻi.Ua mālama ʻia kēia haʻawina e Raymond Mak a me ka hui ma ka palekana oʻO Amoxicillini nā wāhine hāpai.

Ma waena o Iulai 2019 a me Kepakemapa 2021, ua hāʻawi nā kauka ma ka BC Women's Hospital and Health Center i nā pilikia waha i 207 wahine hāpai ma waena o nā makahiki 28 a me 36 mau pule o ka hāpai ʻana.Ma muli o ka loaʻa ʻana o ka helu PEN-FAST o kēia mau wahine he 0, kahi mea hana hoʻoholo lāʻau lapaʻau allergy penicillin i hoʻopaʻa ʻia e manaʻo ana i ka hiki ke loaʻa nā hoʻokolohua ʻili maikaʻi, ua hoʻoholo ʻia lākou āpau i ka haʻahaʻa haʻahaʻa loa.Ua nānā ʻia kēia mau wahine no hoʻokahi hola ma hope o ka lawe ʻana i 500 mg oamoxicillinma ka waha.Lawe nā kauka i kā lākou mau hōʻailona koʻikoʻi i ka hoʻomaka, 15 mau minuke ma hope, a hoʻokahi hola ma hope.ʻO nā maʻi i hōʻike ʻole i nā hōʻailona o ka pane ʻana o IgE-mediated ua hoʻokuʻu ʻia me nā ʻōlelo aʻoaʻo e hoʻokaʻaʻike i ke keʻena keʻena inā hopohopo lākou e pili ana i kahi hopena lohi.

ʻO nā mea nui i loaʻa i kēia haʻawina penei:

1. ʻAʻole he hypersensitivity koke a hoʻopaneʻe paha i 203 o kēia mau kānaka.

2. ʻO nā maʻi ʻehā i koe (1.93%) i loaʻa nā maculopapular maculopapular maikaʻi, i mālama ʻia me ka betamethasone valerate 0.1% ointment a me nā antihistamines.

3. Ua like ka huina pane 1.93% me ka helu helu 1.99% i hōʻike mua ʻia ma ka heluna kanaka makua ʻole hāpai ʻole a me ka helu 2.5% i ka heluna hāpai.

4. ʻAʻohe poʻe i koi i ka epinephrine a i ʻeha paha i ka anaphylaxis, a ʻaʻohe mea i komo i ka haukapila ma muli o ka hoʻāʻo ʻana.

I ka hopena, e like me ka poʻe noiʻi, ʻo ka hōʻemi ʻana i ke koi no ka hoʻāʻo ʻana i ka ʻili penicillin e ʻoki i nā kumukūʻai reagent, ka manawa o ke keʻena, a me ka pono e kipa aku i kahi subspecialist, ʻo ia mau mea e hoʻonui ai i ka mālama maʻi i ka wā o ka hana a me ka hānau ʻana.No ka ʻoi aku ka ikaika o ka hōʻoia, koi ʻia nā noiʻi nui nui.

ref:Mak, R., Zhang, BY, Paquette, V., Erdle, SC, Van Schalkwyk, JE, Wong, T., Watt, M., & Elwood, C. (2022).Ka palekana o ka ho'āʻo waha pololei iā Amoxicillin i nā poʻe maʻi hāpai ma kahi Halemai Tertiary Kanada.Ma ka Journal of Allergy and Clinical Immunology: In Practice.ʻO Elsevier BV.