Maganin rigakafi na gama gari,amoxicillin-clavulanate, na iya inganta ƙananan aikin hanji a cikin yara masu fama da matsalolin motsa jiki, bisa ga binciken da ya bayyana a cikin bugu na Yuni na Jaridar Pediatric Gastroenterology da Nutrition daga Asibitin Yara na Ƙasashen Duniya.
Amoxicillan-clavulanate, kuma aka sani da Augmentin, an fi ba da izini don magance ko rigakafin cututtukan da ƙwayoyin cuta ke haifarwa.Duk da haka, an kuma bayar da rahoton cewa yana ƙara ƙananan motsin hanji a cikin mutane masu lafiya kuma an yi amfani dashi don magance yawan ƙwayar ƙwayar cuta a cikin marasa lafiya masu fama da zawo.
Alamomin ciki na sama kamar tashin zuciya, amai, ciwon ciki, koshi da wuri da ciwon ciki ya zama ruwan dare ga yara.Duk da ci gaban da ake samu a fasaha don gano cututtukan motsi, ana ci gaba da samun ƙarancin magunguna da ake samu don maganin aikin motsa jiki na gastrointestinal tract.
Carlo Di Lorenzo, MD, babban jami'in Gastroenterology, Hepatology da Nutrition a Asibitin Yara na Kasa da kuma daya daga cikin marubutan binciken ya ce "Akwai matukar bukatar sabbin magunguna don magance alamun cututtukan ciki na sama a cikin yara.""Magungunan da ake amfani da su a halin yanzu ana samun su ne kawai akan ƙayyadaddun tsari, suna da tasiri mai mahimmanci ko kuma ba su da tasiri a kan ƙananan hanji da babba."
Don bincika ko amoxicillin-clavulanate na iya zama sabon zaɓi don kula da aikin motar gastrointestinal na sama, masu bincike a Ƙungiyar Yara ta Ƙasa sun bincika marasa lafiya 20 waɗanda aka shirya yin gwajin manometry na antroduodenal.Bayan sanya catheter, tawagar ta lura da motsin kowane yaro yayin azumi na akalla sa'o'i uku.Sannan yaran sun sami kashi daya naamoxicillin-clavulanatea cikin ciki, ko dai sa'a ɗaya kafin cin abinci ko sa'a ɗaya bayan cin abinci sannan a kula da motsin motsi na sa'a ɗaya bayan haka.
Binciken ya nuna cewaamoxicillin-clavulanatehaifar da ƙungiyoyi masu yaduwa a cikin ƙananan hanji, kama da waɗanda aka gani a lokacin duodenal kashi na III na tsarin motsi na tsakiya.Wannan amsa ya faru a yawancin mahalarta binciken a cikin mintuna 10-20 na farko kuma ya fi bayyana lokacin da aka ba da amoxicillin-clavulanate kafin abinci.
"Samar da yanayin duodenal na preprandial na III na iya haɓaka ƙananan ƙwayar hanji, yana tasiri ga microbiome na gut kuma yana taka rawa wajen hana ci gaban ƙananan ƙwayoyin cuta," in ji Dokta Di Lorenzo.
Dokta Di Lorenzo ya ce amoxicillin-clavulanate na iya zama mafi tasiri a cikin marasa lafiya tare da sauye-sauye na duodenal kashi na III, cututtuka na yau da kullum na cututtuka na hanji da kuma wadanda aka ciyar da su kai tsaye a cikin ƙananan hanji tare da gastrojejunal nasojejunal ciyar tubes ko tiyata jejunostomy.
Ko da yake amoxicillin-clavulanate da alama yana shafar ƙananan hanji, tsarin da yake aiki ba a bayyana ba.Dokta Di Lorenzo ya kuma ce akwai yiwuwar yin amfani da amoxicillin-clavulanate a matsayin wakili na prokinetic ya haɗa da shigar da ƙwayoyin cuta, musamman daga ƙwayoyin gram negative kamar E. coli da Klebsiella da haifar da Clostridium difficile colitis.
Har yanzu, ya ce ƙarin binciken fa'idodin amoxicillin-clavulanate na dogon lokaci a cikin yanayin asibiti na ciki yana da kyau."Ƙarancin zaɓuɓɓukan warkewa a halin yanzu na iya tabbatar da amfani da amoxicillin-clavulanate a cikin zaɓaɓɓun marasa lafiya da ke da nau'i mai tsanani na ƙananan hanji dysmotility wanda sauran ayyukan ba su da tasiri," in ji shi.
Lokacin aikawa: Mayu-11-2022