News.pharmnet.com.cn 2021-11-25 Kamfanin dillancin labarai na kasar Sin
A ranar 23 ga Nuwamba, Chongqing GAOJIN Biotechnology Co., Ltd. (wanda ake kira "GAOJIN biotechnology") na cibiyar masana'antar nazarin halittu ta kasa ta Chongqing high tech Zone ta sanar da cewa, bisa ga isotope boron-10, wanda ba shi da rediyoaktif, ya sami nasarar haɓaka. Maganin boron na farko na BPA don muggan ciwace-ciwace irin su melanoma, kansar kwakwalwa da glioma, wanda BNCT ke yi masa magani, wato maganin kama boron neutron Har zuwa mintuna 30 na iya warkar da takamaiman cututtukan daji iri-iri.
BNCT yana daya daga cikin hanyoyin magance ciwon daji mafi ci gaba a duniya.Yana lalata ƙwayoyin cutar kansa ta hanyar ƙwayar cuta ta atomic a cikin ƙwayoyin ƙari.Ka'idar maganinta ita ce: da farko allurar boron mara guba da mara lahani a cikin majiyyaci.Bayan da miyagun ƙwayoyi ya shiga cikin jikin ɗan adam, da sauri ya yi hari kuma ya taru a cikin takamaiman kwayoyin cutar kansa.A wannan lokacin, ana amfani da hasken neutron wanda ba shi da ɗan lahani ga jikin ɗan adam don haskakawa.Bayan neutron ya yi karo da boron da ke shiga cikin sel masu ciwon daji, ana haifar da "maganin nukiliya" mai karfi, yana fitar da ion ray mai tsananin kisa.Kewayon hasken yana da gajere sosai, wanda zai iya kashe kwayoyin cutar kansa kawai ba tare da lalata kyallen da ke kewaye ba.Wannan zaɓin fasaha na rediyo da aka yi niyya wanda ke kashe ƙwayoyin kansa kawai ba tare da lalata kyallen jikin al'ada ba ana kiransa maganin kama boron neutron.
A halin yanzu, BPA boron miyagun ƙwayoyi tare da GAOJIN nazarin halittu code na "gjb01" ya kammala da Pharmaceutical bincike na API da kuma shirye-shirye, da kuma kammala gwajin gwajin sikelin tsari tabbatarwa.Daga baya, ana iya amfani da shi a cikin cibiyoyin R & D na na'urorin BNCT na neutron a kasar Sin don gudanar da bincike mai dacewa, gwaji da aikace-aikacen asibiti.Ya kamata a lura da cewa, samar da matukan jirgi wata hanya ce da ta dace don sauya nasarorin kimiyya da fasaha zuwa karfi mai amfani, kuma nasara ko gazawar masana'antu na nasarorin ya dogara ne kan nasara ko gazawar samar da matukan.
A cikin Maris 2020, steboronine, na'urar BNCT na farko a duniya kuma maganin boron na farko a duniya, an amince da shi don tallatawa a Japan don ci gaban da ba a iya gano shi a cikin gida ko na gida mai maimaita kansa da kansa.Bugu da ƙari, an gudanar da ɗaruruwan gwaje-gwaje na asibiti a cikin ciwace-ciwacen ƙwayoyin cuta, cutar sankarau, ciwon huhu, ciwon huhu, ciwon hanta, da ciwon nono, kuma an sami bayanan warkarwa masu kyau.
Cai Shaohui, mataimakin babban manajan kuma shugaban aikin na GAOJIN ilmin halitta, ya ce gabaɗayan index na "gjb01" ya yi daidai da magungunan steboronine da aka jera a Japan, kuma farashin aikin ya fi girma.Ana sa ran za a yi amfani da shi a asibiti a cikin 2023 kuma ana sa ran za ta zama na farko da aka jera na BNCT na maganin cutar kansa na boron a China.
Cai Shaohui ya ce, "Ingantacciyar yanayin kula da BNCT ba shi da shakka.Tushen shine maganin boron.Manufar bunkasuwar ilmin halitta ta Jin ita ce ta sa jiyya ta BNCT ta kasar Sin ta kai matsayin kan gaba a duniya.Za a iya sarrafa kudin magani yadda ya kamata a kusan yuan dubu 100, ta yadda majinyata masu fama da cutar kansa za su samu magani da kuma samun kudin warkewa."
"Maganin BNCT ana iya kiransa 'lu'u-lu'u a kan kambi' na maganin ciwon daji saboda ƙananan farashi, gajeren hanya na magani (minti 30-60 a kowane lokaci, magani mafi sauri yana iya warkewa sau ɗaya kawai ko sau biyu), alamomi masu yawa da ƙananan. side effects."Wang Jian, Shugaba na GAOJIN ilmin halitta, ya ce, mafi mahimmanci mabuɗin shi ne niyya da kuma shirye-shiryen shirye-shiryen magungunan boron, Yana ƙayyade ko maganin zai iya inganta da kuma magance nau'in ciwon daji.
Lokacin aikawa: Nuwamba-25-2021