Yin amfani da multivitamin a tsakanin masu matsakaicin shekaru, mazan maza yana haifar da raguwa mai sauƙi a cikin ciwon daji, binciken ya gano

"Multivitaminssu ne mafi yawan abincin da ake ci, waɗanda aƙalla kashi uku na manya na Amurka ke ɗauka akai-akai.Matsayin gargajiya na multivitamin yau da kullun shine don hana ƙarancin abinci mai gina jiki.Haɗuwa da mahimman bitamin da ma'adanai waɗanda ke cikin multivitamins na iya yin kama da tsarin abinci mafi koshin lafiya kamar cin 'ya'yan itace da kayan marmari, waɗanda ke da ƙanƙan da kai kuma suna da alaƙa da haɗarin cutar kansa a wasu, amma ba duka ba, nazarin cututtukan cuta.Nazarin lura na dogon lokaci na amfani da multivitamin da wuraren ƙarshen ciwon daji sun kasance marasa daidaituwa.Ya zuwa yau, manyan gwaje-gwajen da bazuwar gwajin gwajin guda ɗaya ko ƙananan adadin bitamin da ma'adanai masu girma na kowane mutum don ciwon daji gabaɗaya sun sami rashin tasiri, "in ji bayanan baya a cikin mujallar."Duk da rashin ingantaccen bayanan gwaji game da fa'idodinmultivitaminsa cikin rigakafin cututtuka na yau da kullun, ciki har da ciwon daji, yawancin maza da mata suna ɗaukar su saboda wannan dalili.

J. Michael Gaziano, MD, MPH, na Brigham da Asibitin Mata da Makarantar Kiwon Lafiya ta Harvard, Boston, (da kuma Editan Gudunmawa,JAMA), kuma abokan aiki sun bincika bayanai daga Nazarin Kiwon Lafiyar Likitoci (PHS) II, babban ma'auni kawai, bazuwar, makafi biyu, gwajin gwajin gwaji na dogon lokaci na multivitamin na yau da kullun a cikin rigakafin cututtuka na yau da kullun.Wannan gwaji ya gayyaci likitocin Amurka maza 14,641 da suka girmi shekaru 50, ciki har da maza 1,312 masu fama da cutar kansa kan tarihin likitancinsu.An shigar da su a cikin nazarin multivitamin wanda ya fara a 1997 tare da jiyya da kuma biyo baya har zuwa Yuni 1, 2011. Mahalarta sun sami multivitamin yau da kullum ko daidai placebo.Sakamakon farko da aka auna don binciken shine jimillar ciwon daji (ban da ciwon daji na fata wanda ba melanoma ba), tare da prostate, colorectal, da sauran cututtukan daji na musamman a tsakanin wuraren ƙarshe na biyu.

An bi mahalarta PHS II na matsakaicin shekaru 11.2.A lokacin jiyya na multivitamin, an sami 2,669 da aka tabbatar sun kamu da cutar kansa, ciki har da 1,373 na cutar sankara ta prostate da kuma 210 na ciwon daji na colorectal, tare da wasu mazan suna fuskantar al'amura da yawa.Jimlar 2,757 (kashi 18.8) maza sun mutu yayin bin diddigin, ciki har da 859 (kashi 5.9) saboda ciwon daji.Binciken bayanan ya nuna cewa maza masu shan multivitamin sun sami raguwar kashi 8 cikin 100 na yawan kamuwa da cutar kansa.Maza masu shan bitamin multivitamin sun sami irin wannan raguwa a cikin jimillar ciwon daji na epithelial cell.Kusan rabin duk cutar kansar da suka faru sune ciwon gurguwar prostate, yawancinsu sun kasance matakin farko.Masu binciken ba su sami wani tasiri na multivitamin akan kansar prostate ba, yayin da multivitamin ya rage yawan haɗarin ciwon daji gaba ɗaya ban da ciwon gurguwar prostate.Ba a sami raguwar ƙididdiga mai mahimmanci a cikin takamaiman cutar kansar mutum ɗaya ba, gami da launin launi, huhu, da kansar mafitsara, ko a cikin mace-macen kansar.

Amfani da multivitamin na yau da kullun kuma yana da alaƙa da raguwar cutar kansa gabaɗaya tsakanin maza 1,312 waɗanda ke da asalin tarihin kansa, amma wannan sakamakon bai bambanta sosai da wanda aka gani a tsakanin maza 13,329 da farko ba tare da cutar kansa ba.

Masu binciken sun lura cewa jimlar yawan ciwon daji a cikin gwajin su na iya yin tasiri ta hanyar karuwar sa ido na musamman na prostate-specific antigen (PSA) da kuma cututtukan da suka biyo baya na ciwon gurguwar prostate yayin bin PHS II da suka fara a ƙarshen 1990s.“Kusan rabin duk cututtukan da aka tabbatar da su a cikin PHS II sune ciwon gurguwar prostate, wanda mafi yawansu sune matakin farko, ƙananan ciwon gurguwar ƙwayar cuta tare da yawan rayuwa.Matsakaicin raguwa a cikin jimlar ciwon daji in ban da kansar prostate yana nuna cewa amfani da multivitamin yau da kullun na iya samun fa'ida mafi girma akan ƙarin binciken cutar kansa na asibiti.

Marubutan sun kara da cewa ko da yake yawancin bitamin da ma'adanai masu yawa da ke ƙunshe a cikin binciken multivitamin na PHS II sun ƙaddamar da ayyukan chemopreventive, yana da wuya a iya tantance kowane nau'i na tasiri ta hanyar abin da mutum ko ma'auni na multivitamin da aka gwada na iya rage haɗarin ciwon daji."Raguwar jimlar haɗarin ciwon daji a cikin PHS II yana ba da hujjar cewa babban haɗin haɗin bitamin da ma'adanai masu ƙarancin adadin da ke cikin PHS II multivitamin, maimakon girmamawa kan gwajin bitamin da ma'adinai da aka gwada a baya, na iya zama mafi mahimmanci don rigakafin cutar kansa. .Matsayin dabarun rigakafin cutar kansa da ke mai da hankali kan abinci kamar cin 'ya'yan itace da kayan marmari da aka yi niyya ya kasance mai ban sha'awa amma ba a tabbatar da shi ba idan aka yi la'akari da rashin daidaiton shaidar cututtukan cututtukan da rashin ingantaccen bayanan gwaji."

"Ko da yake babban dalilin da za a dauki multivitamins shine don hana rashin abinci mai gina jiki, waɗannan bayanan suna ba da goyon baya ga yiwuwar yin amfani da kayan abinci na multivitamin a cikin rigakafin ciwon daji a cikin tsofaffi da maza," masu binciken sun kammala.