Kev siv multivitamin ntawm cov hnub nyoog nruab nrab, cov txiv neej laus ua rau txo qis hauv kev mob qog noj ntshav, kev tshawb fawb pom

“Multivitaminsyog cov khoom noj khoom haus ntau tshaj plaws, tsis tu ncua los ntawm tsawg kawg ib feem peb ntawm cov neeg laus hauv Asmeskas.Lub luag haujlwm tseem ceeb ntawm ib hnub multivitamin yog los tiv thaiv kev noj zaub mov tsis txaus.Kev sib xyaw ntawm cov vitamins thiab cov zaub mov tseem ceeb uas muaj nyob rau hauv multivitamin tuaj yeem ua rau pom kev noj qab haus huv zoo dua qub xws li txiv hmab txiv ntoo thiab zaub kom tsawg, uas tau muaj kev sib haum xeeb thiab cuam tshuam nrog kev pheej hmoo mob qog noj ntshav hauv qee qhov, tab sis tsis yog tag nrho, kev tshawb fawb txog kab mob.Kev soj ntsuam kev tshawb fawb ntawm kev siv cov vitamin mus sij hawm ntev thiab cov ntsiab lus mob qog noj ntshav tsis sib haum.Txog rau tam sim no, qhov kev sim loj loj hauv kev sim ntsuas ib zaug lossis tsawg ntawm cov tshuaj ntau dua ib tus neeg cov vitamins thiab minerals rau mob qog noj ntshav feem ntau pom tias tsis muaj txiaj ntsig," hais hauv cov ntaub ntawv keeb kwm yav dhau los hauv phau ntawv journal."Txawm hais tias tsis muaj cov ntaub ntawv hais txog cov txiaj ntsig ntawmmultivitaminsHauv kev tiv thaiv kab mob ntev, suav nrog mob qog noj ntshav, ntau tus txiv neej thiab poj niam coj lawv rau qhov tseeb vim li no. "

J. Michael Gaziano, MD, MPH, ntawm Brigham thiab Women's Hospital thiab Harvard Medical School, Boston, (thiab kuj Pab Koom Tes Editor,JAMA), thiab cov npoj yaig tau txheeb xyuas cov ntaub ntawv los ntawm Cov Kws Kho Mob Kev Tshawb Fawb Kev Noj Qab Haus Huv (PHS) II, tsuas yog loj-loj, randomized, ob qhov muag tsis pom kev, cov tshuaj placebo-tswj tshuaj ntsuam xyuas cov teebmeem mus sij hawm ntev ntawm cov tshuaj multivitamin hauv kev tiv thaiv kab mob ntev.Qhov kev sim no tau caw 14,641 tus txiv neej Asmeskas cov kws kho mob laus dua 50 xyoo, suav nrog 1,312 tus txiv neej mob qog noj ntshav ntawm lawv cov keeb kwm kho mob.Lawv tau cuv npe kawm hauv ib txoj kev tshawb fawb multivitamin uas tau pib xyoo 1997 nrog kev kho mob thiab ua raws li lub Rau Hli 1, 2011. Cov neeg koom tau txais ib hnub multivitamin lossis sib npaug ntawm cov placebo.Thawj qhov ntsuas tau rau txoj kev tshawb no yog mob qog noj ntshav tag nrho (tsis suav nrog cov qog nqaij hlav nonmelanoma), nrog rau prostate, mob plab, thiab lwm yam mob qog noj ntshav ntawm qhov chaw thib ob.

Cov neeg koom nrog PHS II tau ua raws li qhov nruab nrab ntawm 11.2 xyoo.Thaum lub sij hawm kho multivitamin, muaj 2,669 tus neeg uas tau lees paub tias mob qog noj ntshav, suav nrog 1,373 tus neeg mob qog noj ntshav prostate thiab 210 tus neeg mob qog nqaij hlav hauv plab, nrog qee tus txiv neej ntsib ntau yam xwm txheej.Tag nrho ntawm 2,757 (18.8 feem pua) cov txiv neej tuag thaum taug qab, suav nrog 859 (5.9 feem pua) vim mob qog noj ntshav.Kev tshuaj xyuas ntawm cov ntaub ntawv qhia tau hais tias cov txiv neej noj cov tshuaj multivitamin muaj qhov txo qis ntawm 8 feem pua ​​​​ntawm tag nrho cov mob qog noj ntshav.Cov txiv neej noj cov tshuaj multivitamin muaj qhov txo qis hauv cov qog nqaij hlav epithelial tag nrho.Kwv yees li ib nrab ntawm tag nrho cov xwm txheej mob qog noj ntshav yog mob qog noj ntshav prostate, ntau yam uas yog theem pib.Cov kws tshawb fawb pom tias tsis muaj txiaj ntsig ntawm multivitamin rau mob qog noj ntshav prostate, thaum lub multivitamin txo qis kev pheej hmoo ntawm tag nrho cov qog noj ntshav tsis suav nrog mob qog noj ntshav prostate.Tsis muaj ib qho kev txo qis hauv cov qog nqaij hlav hauv ib qho chaw tshwj xeeb, suav nrog mob qog noj ntshav, mob ntsws, thiab mob qog noj ntshav, lossis mob qog noj ntshav.

Kev siv cov vitamin niaj hnub kuj tseem cuam tshuam nrog kev txo qis ntawm tag nrho cov qog noj ntshav ntawm 1,312 tus txiv neej uas muaj keeb kwm keeb kwm ntawm mob qog noj ntshav, tab sis qhov tshwm sim no tsis txawv qhov txawv ntawm qhov pom ntawm 13,329 tus txiv neej pib tsis muaj mob qog noj ntshav.

Cov kws tshawb fawb tau sau tseg tias tag nrho cov qog nqaij hlav cancer hauv lawv qhov kev sim yuav cuam tshuam los ntawm kev soj ntsuam ntau ntxiv rau prostate-specific antigen (PSA) thiab tom qab kuaj mob qog noj ntshav thaum lub sij hawm PHS II rov qab pib thaum xyoo 1990s."Kwv yees li ib nrab ntawm tag nrho cov mob qog noj ntshav hauv PHS II yog mob qog noj ntshav prostate, uas feem coob yog cov theem ua ntej, qib qis dua cov qog nqaij hlav prostate nrog cov ciaj sia taus.Qhov tseem ceeb txo qis ntawm tag nrho cov qog nqaij hlav qog nqaij hlav qog nqaij hlav prostate qhia tias kev siv cov vitamin txhua hnub tuaj yeem muaj txiaj ntsig zoo dua rau kev kuaj mob qog noj ntshav ntau dua. "

Cov kws sau ntawv ntxiv tias txawm hais tias ntau tus tib neeg cov vitamins thiab minerals uas muaj nyob rau hauv PHS II multivitamin txoj kev tshawb fawb muaj cov luag hauj lwm chemopreventive, nws yog ib qho nyuaj rau kev txheeb xyuas ib qho kev cuam tshuam los ntawm ib tus neeg los yog ntau yam ntawm lawv cov multivitamin kuaj yuav txo qis kev pheej hmoo mob qog noj ntshav."Kev txo qis ntawm tag nrho cov kev pheej hmoo mob qog noj ntshav hauv PHS II tau sib cav tias kev sib xyaw dav dav ntawm cov tshuaj vitamins thiab cov zaub mov muaj nyob hauv PHS II multivitamin, tsis yog qhov tseem ceeb rau yav dhau los kev sim tshuaj ntau cov vitamins thiab minerals, tej zaum yuav yog qhov tseem ceeb rau kev tiv thaiv mob qog noj ntshav. .… Lub luag haujlwm ntawm kev tiv thaiv kab mob qog noj ntshav xws li kev noj cov txiv hmab txiv ntoo thiab zaub tseem muaj kev cia siab tab sis tsis muaj pov thawj tau muab cov pov thawj tsis sib xws thiab tsis muaj cov ntaub ntawv sim sim. "

"Txawm hais tias qhov laj thawj tseem ceeb ntawm kev noj cov tshuaj multivitamin yog los tiv thaiv kev noj zaub mov tsis txaus, cov ntaub ntawv no muab kev txhawb nqa rau kev siv cov tshuaj multivitamin hauv kev tiv thaiv kev mob qog noj ntshav hauv cov txiv neej hnub nyoog nruab nrab thiab cov laus," cov kws tshawb fawb xaus.