Canada: Cov poj niam cev xeeb tub, muaj keeb kwm ntawm kev tsis haum tshuaj penicillin tuaj yeem ua tiav qhov ncauj ncaj qhaamoxicillinkev sib tw yam tsis tas yuav tsum tau kuaj daim tawv nqaij ua ntej, hais tias ib tsab xov xwm luam tawm hauvPhau ntawv Journal of Allergy and Clinical Immunology: In Practice.
Hauv ntau tus neeg mob, kev tsis haum tshuaj penicillin de-labeling tau pom tias muaj kev nyab xeeb thiab ua tiav rau cov tib neeg uas muaj kev pheej hmoo tsawg.Kev ntsuam xyuas pom tau tias ntau dua 90% ntawm cov neeg tsis ua xua hauv thawj qhov chaw.Txawm hais tias qhov tseeb tias cev xeeb tub tsis ua rau muaj kev pheej hmoo ntawm kev ua xua rau penicillin, cov poj niam cev xeeb tub feem ntau raug tshem tawm los ntawm kev tshawb fawb feem ntau.Txoj kev tshawb no yog ua los ntawm Raymond Mak thiab pab neeg ntawm kev nyab xeeb ntawmAmoxicillinhauv cov poj niam cev xeeb tub.
Nyob nruab nrab ntawm Lub Xya Hli 2019 txog Lub Cuaj Hli 2021, cov kws kho mob ntawm BC Women's Hospital thiab Health Center tau teeb tsa qhov ncauj ncaj qha rau 207 tus poj niam cev xeeb tub ntawm hnub nyoog 28 thiab 36 lub lis piam ntawm cev xeeb tub.Vim tias cov poj niam no txhua tus tau PEN-FAST tus qhab nia ntawm 0, qhov pov thawj, taw qhia ntawm kev saib xyuas penicillin tsis haum tshuaj kho mob cov cuab yeej txiav txim siab uas cia siab tias yuav muaj kev kuaj tawv nqaij zoo, lawv txhua tus tau txiav txim siab tsis tshua muaj kev pheej hmoo.Cov poj niam no tau pom nyob rau ib teev tom qab noj 500 mg ntawmamoxicillinhais lus.Cov kws kho mob tau coj lawv cov cim tseem ceeb thaum pib, 15 feeb tom qab, thiab ib teev tom qab ntawd.Cov neeg mob uas tsis pom cov tsos mob ntawm IgE-kev kho mob cov lus teb tau raug tshem tawm nrog cov lus qhia hu rau lub tsev kho mob yog tias lawv txhawj xeeb txog qhov kev tshwm sim qeeb.
Cov kev tshawb pom tseem ceeb ntawm txoj kev tshawb fawb no yog raws li nram no:
1. Tsis muaj qhov tshwm sim tam sim lossis qeeb qeeb hauv 203 ntawm cov neeg no.
2. Cov neeg mob uas tseem tshuav plaub (1.93%) muaj benign maculopapular pob, uas tau kho nrog betamethasone valerate 0.1% tshuaj pleev thiab tshuaj tiv thaiv.
3. Cov lus teb 1.93% piv rau yav dhau los tau tshaj tawm 1.99% tus nqi hauv cov neeg laus tsis cev xeeb tub thiab 2.5% tus nqi ntawm cov neeg cev xeeb tub.
4. Tsis muaj cov neeg uas xav tau epinephrine lossis raug mob anaphylaxis, thiab tsis muaj leej twg tau mus pw hauv tsev kho mob vim qhov kev sim.
Hauv kev xaus, raws li cov kws tshawb fawb, txo qhov yuav tsum tau rau kev kuaj tawv nqaij penicillin yuav txo cov nqi reagent, lub sij hawm kho mob, thiab qhov yuav tsum tau mus ntsib tus kws kho mob tshwj xeeb, tag nrho cov no yuav txhim kho kev saib xyuas tus neeg mob thaum lub sij hawm ua hauj lwm thiab kev yug me nyuam.Txhawm rau kom muaj pov thawj muaj zog ntxiv, yuav tsum muaj kev tshawb nrhiav loj ntxiv.
ref:Mak, R., Zhang, BY, Paquette, V., Erdle, SC, Van Schalkwyk, JE, Wong, T., Watt, M., & Elwood, C. (2022).Kev Nyab Xeeb ntawm Kev Sib Tw Direct Oral rau Amoxicillin hauv Cov Neeg Mob Cev Xeeb Tub ntawm Canadian Tertiary Tsev Kho Mob.Nyob rau hauv Phau ntawv Journal of Allergy and Clinical Immunology: In Practice.Elsevier BV.
Lub sij hawm xa tuaj: Plaub Hlis-25-2022