News.pharmnet.com.cn 2021-11-25 China News Network
Na Nọvemba 23, Chongqing GAOJIN Biotechnology Co., Ltd. (nke a na-akpọ "GAOJIN biotechnology") nke ụlọ ọrụ mmepụta ihe nke mba dị na Chongqing high tech Zone kwupụtara na dabere na isotope boron-10 na-abụghị redioaktivu, ọ rụpụtala nke ọma. ọgwụ boron nke mbụ BPA maka etuto ọjọọ dị ka melanoma, ọrịa kansa ụbụrụ na glioma, bụ nke BNCT na-agwọ ya, ya bụ ọgwụgwọ ijide boron neutron ruo nkeji iri atọ nwere ike gwọọ ọrịa cancer dị iche iche.
BNCT bụ otu n'ime usoro ọgwụgwọ ọrịa kansa kachasị elu n'ụwa.Ọ na-ebibi mkpụrụ ndụ kansa site na mmeghachi omume nuklia nke atọ na mkpụrụ ndụ tumo.Usoro ọgwụgwọ ya bụ: buru ụzọ gbanye boron nke na-adịghị egbu egbu na nke na-adịghị emerụ ahụ nke nwere ọgwụ n'ime onye ọrịa.Mgbe ọgwụ ahụ batara n'ime ahụ mmadụ, ọ na-atụ anya ngwa ngwa ma na-agbakọta na mkpụrụ ndụ kansa kpọmkwem.N'oge a, a na-eji ụzarị neutron na-emebi obere ahụ mmadụ maka irradiation.Mgbe neutron dakọtara na boron na-abanye na mkpụrụ ndụ kansa, a na-emepụta "mmeghachi omume nuklia" siri ike, na-ahapụ ion ray dị arọ na-egbu egbu nke ukwuu.Ogologo ray dị mkpụmkpụ, nke nwere ike igbu mkpụrụ ndụ kansa na-emebighị anụ ahụ gbara ya gburugburu.Teknụzụ redio ọgwụgwọ a ezubere iche ezubere iche nke na-egbu naanị mkpụrụ ndụ kansa na-emebighị anụ ahụ nkịtị ka a na-akpọ ọgwụgwọ ijide boron neutron.
Ka ọ dị ugbu a, ọgwụ boron BPA nwere koodu ndụ GAOJIN nke “gjb01” emechaala nyocha ọgwụ nke API na nkwadebe, wee mechaa nyocha usoro nkwadebe ọnụ ọgụgụ pilot.Mgbe e mesịrị, enwere ike iji ya na ụlọ ọrụ R & D nke BNCT neutron therapy ngwaọrụ na China iji mee nchọpụta dị mkpa, nnwale na ngwa ụlọ ọgwụ.Ọ bụ ihe kwesịrị ịrịba ama na pilot mmepụta bụ ihe dị mkpa njikọ maka mgbanwe nke sayensị na nkà na ụzụ rụzuru n'ime na-arụpụta ike, na ihe ịga nke ọma ma ọ bụ ọdịda nke ulo oru nke rụzuru tumadi dabere na ihe ịga nke ọma ma ọ bụ ọdịda nke pilot mmepụta.
Na Machị 2020, steboronine, ngwaọrụ BNCT izizi n'ụwa na ọgwụ boron nke mbụ n'ụwa, ka akwadoro maka ịre ahịa na Japan maka ọrịa kansa isi na olu na-emegharị emegharị na mpaghara.Tụkwasị na nke ahụ, e mewo ọtụtụ narị ule ụlọ ọgwụ na etuto ụbụrụ, melanoma na-adịghị mma, ọrịa cancer akpa ume, pleural mesothelioma, ọrịa imeju, na ọrịa ara ara, na enwetawo ezi data ọgwụgwọ.
Cai Shaohui, osote onye isi njikwa na onye ndu oru ngo nke GAOJIN biology, kwuru na mkpokọta “gjb01″” dabara na ọgwụ steboronine edepụtara na Japan, yana arụmọrụ ọnụ ya dị elu.A na-atụ anya na a ga-eji ya na ụlọ ọgwụ na 2023 ma na-atụ anya na ọ ga-abụ nke mbụ edepụtara BNCT ọgwụ mgbochi ọrịa kansa boron na China.
Cai Shaohui kwuru, "ọdịdị elu nke ọgwụgwọ BNCT enweghị obi abụọ.Isi ya bụ ọgwụ boron.Ebumnuche nke usoro ihe ọmụmụ Jin dị elu bụ ime ka ọgwụgwọ China BNCT ruo ọkwa kachasị elu n'ụwa.Enwere ike ịchịkwa ọnụ ahịa ọgwụgwọ nke ọma na ihe dị ka puku yuan 100, ka ndị ọrịa nwere ọrịa kansa nwee ike nweta ọgwụgwọ ahụike ma nwee ego iji gwọọ ya. ”
"Ngwọta BNCT nwere ike ịkpọ 'pearl na okpueze' nke ọgwụgwọ ọrịa cancer n'ihi na ọ dị ọnụ ala, usoro ọgwụgwọ dị mkpirikpi (nkeji 30-60 n'oge ọ bụla, ọgwụgwọ kachasị ngwa ngwa nwere ike ịgwọ naanị otu ugboro ma ọ bụ ugboro abụọ), ihe ngosi sara mbara na nke dị ala. mmetụta ọjọọ."Wang Jian, CEO nke GAOJIN bayoloji, kwuru na isi ihe kacha mkpa bụ ezubere iche na nkwadebe usoro nke boron ọgwụ, Ọ na-ekpebi ma ọgwụgwọ nwere ike mma na n'ụzọ ziri ezi na-emeso ndị ọzọ ụdị ọrịa cancer.
Oge nzipu: Nov-25-2021