Komiti ya akatswiri a FDA imathandizira kulembedwa kwa methadone Xinguan oral drug

Chitsime: yaozhi.com

Chiyambi: malinga ndi zomwe zapezeka posachedwa azachipatala, molnupiravir imatha kuchepetsa chiwopsezo kapena kufa ndi 30%.

Pa Novembara 30, gulu la FDA linavota 13:10 kuti ivomereze ntchito ya EUA ya molnupiravir, mankhwala apakamwa atsopano a MSD.Ngati kuvomerezedwa, bola ngati pali malangizo a dokotala, odwala omwe ali ndi kachilomboka kapena anthu omwe ali ndi kachilomboka amatha kugwiritsa ntchito mankhwalawa kunyumba osapita kuchipatala kapena kuchipatala kuti akalandire chithandizo ngati mankhwala a monoclonal antibody.

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Molnupiravir ndi mankhwala atsopano opangidwa ndi mosadon mogwirizana ndi kampani ya Ridgeback biotherapy.M'mbuyomu adalandira chilolezo chogwiritsa ntchito mwadzidzidzi ku UK, koma zomwe zatulutsidwa posachedwa zachipatala zikuwonetsa kuti chiwongola dzanja chatsika kwambiri.

Malinga ndi chilengezo cha MSD sabata yatha, zoyeserera zomaliza zidawonetsa kuti anthu 68 mgulu la placebo 699 adagonekedwa mchipatala kapena kumwalira, pomwe odwala 48 okha mwa 709 omwe adatenga monapiravir adawonongekanso, zomwe zidachepetsa chiwopsezo chogonekedwa / kufa kuchokera ku 9.7% mpaka 6.8%, ndipo chiwopsezo chochepetsera chiwopsezo chinafika 30%.Ndikoyenera kutchula kuti anthu 9 adamwalira m'gulu la placebo ndipo m'modzi yekha pagulu la molnupiravir.

Komabe, komiti ya akatswiri ku US FDA idavotera 13 mpaka 10 kuti athandizire molnupiravir, mankhwala oletsa mavairasi a methadone, ponena kuti phindu lake limaposa kuopsa kwake.A FDA sakakamizidwa kutsatira malingaliro a komiti, koma nthawi zambiri amasankha kuwatsatira.

Kuphatikiza apo, Pfizer akufunanso kuvomerezedwa ndi FDA pamankhwala ake atsopano a korona.The gawo III chipatala kafukufuku paxlovid, korona watsopano m`kamwa mankhwala, zikusonyeza kuti chiopsezo cha chipatala kapena imfa akhoza kuchepetsedwa pafupifupi 89% odwala ndi wofatsa ndi zolimbitsa korona watsopano mkati mwa masiku atatu matenda, amene angafanane ndi achire zotsatira. kusokoneza ma antibodies a korona watsopano.

Mkonzi wodalirika: Liuli