Vitamini C ingathandize kuthetsa zotsatira zoyipa za mankhwala a chemotherapy

Kafukufuku wa makoswe akusonyeza kuti kutengavitamini CZingathandize kuthana ndi kuwonongeka kwa minofu, zotsatira zodziwika za mankhwala a chemotherapy doxorubicin.Ngakhale kuti maphunziro a zachipatala amafunikira kuti adziwe chitetezo ndi mphamvu ya kumwa vitamini C panthawi ya mankhwala a doxorubicin, zomwe zapeza zikusonyeza kuti vitamini C ikhoza kukhala mwayi wodalirika wochepetsera zovuta zina za mankhwalawa.
Zomwe tapeza zikuwonetsa kuti vitamini C ndi njira yothandizira yomwe ingathandizire kuchiza matenda a minofu yapambuyo potsatira chithandizo cha doxorubicin, potero kumapangitsa kuti magwiridwe antchito azitha komanso moyo wabwino komanso kuchepetsa kufa.
Antonio Viana do Nascimento Filho, M.Sc., Universidad Nova de Julio (UNINOVE), Brazil, mlembi woyamba wa kafukufukuyu, apereka zomwe apeza pamsonkhano wapachaka wa American Physiological Society pamsonkhano wa 2022 Experimental Biology (EB) ku Philadelphia, Epulo 2-5.

Doxorubicin ndi mankhwala a anthracycline chemotherapy omwe amagwiritsidwa ntchito nthawi zambiri ndi mankhwala ena a chemotherapy pochiza khansa ya m'mawere, khansa ya chikhodzodzo, lymphoma, leukemia, ndi mitundu ina yambiri ya khansa.Ngakhale ndi mankhwala oletsa khansa, doxorubicin imatha kuyambitsa zovuta zamtima komanso kuwonongeka kwa minofu, zomwe zimakhala ndi zotsatira zokhalitsa pakukula kwamphamvu ndi moyo wa otsala.
Zotsatira zoyipazi zimaganiziridwa kuti zimayamba chifukwa cha kuchuluka kwa zinthu zotulutsa mpweya wa okosijeni kapena "ma free radicals" m'thupi.Vitamini Cndi antioxidant yachilengedwe yomwe ingathandize kuchepetsa kupsinjika kwa okosijeni, mtundu wa zowonongeka zomwe zimayambitsidwa ndi ma free radicals.
Pakafukufuku wam'mbuyomu ndi University of Manitoba ku Canada, gululo lidapeza kuti vitamini C imawongolera zowunikira zaumoyo wamtima komanso kupulumuka kwa makoswe opatsidwa doxorubicin, makamaka pochepetsa kupsinjika kwa okosijeni ndi kutupa.Mu kafukufuku watsopano, adawunika ngati vitamini C ingathandizenso kupewa zotsatira zoyipa za doxorubicin pamitsempha ya chigoba.

Ofufuzawo anayerekezera chigoba cha minofu ndi zizindikiro za kupsinjika kwa okosijeni m'magulu anayi a makoswe, aliyense wa 8 kwa 10 nyama.Gulu limodzi linatenga onse awirivitamini Cndi doxorubicin, gulu lachiwiri linangotenga vitamini C, gulu lachitatu linangotenga doxorubicin, ndipo gulu lachinayi silinatengenso.Mbewa zopatsidwa vitamini C ndi doxorubicin zinasonyeza umboni wa kuchepa kwa kupsinjika kwa okosijeni ndi minofu yabwino poyerekeza ndi mbewa zopatsidwa doxorubicin koma osati vitamini C.
"Ndizosangalatsa kuti prophylactic ndi concomitant mankhwala ndi vitamini C kuperekedwa kwa sabata limodzi doxorubicin ndi milungu iwiri pambuyo doxorubicin zokwanira kuchepetsa zotsatira za mankhwala pa chigoba minofu, potero kuchepetsa Huge zotsatira zabwino pa chigoba minofu.Kuphunzira za thanzi la nyama,” akutero Nascimento Filho.” Ntchito yathu imasonyeza kuti chithandizo cha vitamini C chimachepetsa kutayika kwa minofu ndi kuwongolera zizindikiro zambiri za kusalinganika kwamphamvu kwaufulu kwa makoswe amene analandira doxorubicin.”

Asayansiwo adanenanso kuti kafukufuku wowonjezereka, kuphatikizapo mayesero achipatala, amafunikira kuti atsimikizire ngati kutenga vitamini C panthawi ya chithandizo cha doxorubicin n'kothandiza kwa odwala komanso kudziwa mlingo woyenera ndi nthawi yake.Kafukufuku wam'mbuyomu akuwonetsa kuti vitamini C ikhoza kusokoneza zotsatira za mankhwala a chemotherapy, kotero odwala samalangizidwa kuti amwe mavitamini C owonjezera panthawi ya chithandizo cha khansa pokhapokha atauzidwa ndi dokotala.