Amakuru.pharmnet.com.cn 2021-11-25 Umuyoboro wamakuru wubushinwa
Ku ya 23 Ugushyingo, Chongqing GAOJIN Biotechnology Co., Ltd. umuti wa mbere wa BPA boron kubyimba bibi nka melanoma, kanseri yubwonko na glioma, byavuwe na BNCT, aribyo kuvura boron neutron gufata imiti Mugihe cyiminota 30 gishobora gukiza kanseri zitandukanye.
BNCT ni bumwe mu buryo bugezweho bwo kuvura kanseri ku isi.Isenya kanseri ya kanseri ikoresheje reaction ya kirimbuzi ya selile.Ihame ryayo ryo kuvura ni: banza utere boron idafite uburozi kandi itagira ingaruka zirimo imiti mumurwayi.Umuti umaze kwinjira mumubiri wumuntu, uhita wibasira kandi ukarundarunda muri kanseri yihariye.Muri iki gihe, imirasire ya neutron yangiza umubiri muto wumuntu irakoreshwa.Nyuma ya neutron igonganye na boron yinjira mungirangingo ya kanseri, havuka "reaction reaction" ikomeye, ikarekura imirasire yica cyane.Urwego rw'imirasire ni ngufi cyane, rushobora kwica kanseri ya kanseri gusa ntirwangize ingirangingo.Ubu buryo bwo guhitamo radiotherapi yica gusa kanseri yangiza uturemangingo dusanzwe bita boron neutron gufata imiti.
Kugeza ubu, imiti ya BPA hamwe na GAOJIN code ya biologiya ya “gjb01 ″ yarangije ubushakashatsi mu bya farumasi ya API no kuyitegura, kandi irangiza igenzura ryikigereranyo.Nyuma, irashobora gukoreshwa mubigo bya R & D bya BNCT ibikoresho bya neutron bivura mubushinwa kugirango bikore ubushakashatsi, ubushakashatsi hamwe nubuvuzi.Twabibutsa ko umusaruro wicyitegererezo ari ihuriro rikenewe muguhindura ibyagezweho mubumenyi na tekinoloji mu mbaraga zitanga umusaruro, kandi gutsinda cyangwa kunanirwa kwinganda mubikorwa byagezweho ahanini biterwa nubutsinzi cyangwa gutsindwa kwicyitegererezo.
Muri Werurwe 2020, steboronine, igikoresho cya mbere cya BNCT ku isi ndetse n’umuti wa mbere wa boron ku isi, yemerewe gucururizwa mu Buyapani kubera kanseri y’umutwe ndetse na kanseri yo mu ijosi.Byongeye kandi, amagana y’amavuriro yakozwe mu bibyimba byo mu bwonko, melanoma mbi, kanseri y'ibihaha, mesothelioma, kanseri y'umwijima, na kanseri y'ibere, kandi habonetse amakuru meza yo gukiza.
Cai Shaohui, umuyobozi mukuru wungirije akaba n’umuyobozi w’umushinga w’ibinyabuzima bya GAOJIN, yavuze ko igipimo rusange cya “gjb01 ″ gihuza rwose n’ibiyobyabwenge bya steboronine biri mu Buyapani, kandi imikorere y’ibiciro ikaba myinshi.Biteganijwe ko izakoreshwa mu mavuriro mu 2023 kandi biteganijwe ko izaba imiti ya mbere ya BNCT irwanya kanseri mu Bushinwa.
Cai Shaohui yagize ati, "imiterere igezweho yo kuvura BNCT ntagushidikanya.Intangiriro ni imiti ya boron.Intego yibinyabuzima bya Jin bihanitse ni ukugira ngo Ubushinwa buvura BNCT bugere ku rwego rwa mbere ku isi.Amafaranga yo kwivuza arashobora kugenzurwa neza hafi ibihumbi 100, kugirango abarwayi ba kanseri bashobore kwivuza kandi bafite amafaranga yo gukiza. ”
“Ubuvuzi bwa BNCT bushobora kwitwa 'isaro ku ikamba' ryo kuvura kanseri kubera igiciro cyayo gito, igihe gito cyo kuvura (iminota 30-60 buri mwanya, ubuvuzi bwihuse burashobora gukira rimwe cyangwa kabiri), ibimenyetso byinshi kandi biri hasi ingaruka mbi. ”Wang Jian, umuyobozi mukuru w’ibinyabuzima bya GAOJIN, yavuze ko urufunguzo rw’ingenzi ari uburyo bwo kurwanya no gutegura imiti ya boron, Igena niba ubuvuzi bushobora kuvura neza kandi neza ubwoko bwa kanseri.
Igihe cyo kohereza: Ugushyingo-25-2021