Inyanya zisanzwe zitanga umusarurovitamine D.preursors.Gufunga inzira yo kuyihindura mubindi miti irashobora gutuma habaho kwirundanya kwa preursor.
Ibihingwa byinyanya byahinduwe na gen bitanga vitamine D ibanziriza umunsi umwe bishobora gutanga inyamanswa yintungamubiri zingenzi.
Abantu bagera kuri miliyari 1 ntibabona vitamine D ihagije - indwara ishobora gutera ibibazo bitandukanye byubuzima, harimo n’ubudahangarwa bw’umubiri ndetse n’imitsi.vitamine D.biva mu bikomoka ku nyamaswa nk'amagi, inyama, n'amata.
Igihe inyanya zahinduwe na gene zasobanuwe mu bimera bya Kamere ku ya 23 Gicurasi zagaragaye ku mucyo wa ultraviolet muri laboratoire, bamwe mu babanjirije bita vitamine D3 bahinduye vitamine D3.Ariko ibyo bimera ntibiratezwa imbere ngo bikoreshwe mu bucuruzi, kandi ntibizwi. uko bazitwara mugihe bakuze hanze.
Icyakora, umuhanga mu binyabuzima witwa Johnathan Napier wo mu bushakashatsi bwa Rothamsted i Harpenden, mu Bwongereza, avuga ko uru ari urugero rwiza kandi rudasanzwe rwo gukoresha gene mu rwego rwo kuzamura imirire y’ibihingwa.Bisaba gusobanukirwa byimbitse ku binyabuzima by’inyanya. ”Urashobora guhindura gusa ibyo urumva. "Ati:" Kandi ni ukubera ko twumva ibinyabuzima dushobora gukora ubu buryo bwo gutabara. "
Guhindura ibisekuru ni tekinike ituma abashakashatsi bahindura intego kuri genome y’ibinyabuzima kandi bakaba bashimwa nkuburyo bushoboka bwo guteza imbere ibihingwa byiza.Mu gihe ibihingwa byahinduwe mu buryo bwa genoside bikozwe no kwinjiza gen muri genome y’igihingwa ubusanzwe bigomba gukurikiranwa cyane n’ubuyobozi bwa leta, ibihugu byinshi byahinduye gahunda yo guhinga genome-mugihe ihindurwa ryoroshye kandi ihinduka ryavuyemo rishobora no kuba ihinduka ryimiterere-karemano.
Ariko Napier yavuze ko hari uburyo buke bwo gukoresha ubu bwoko bwa gen kugirango uhindure imirire yibihingwa.Mu gihe guhindura gene bishobora gukoreshwa muguhagarika ingirabuzimafatizo muburyo bugirira akamaro abaguzi-urugero, mugukuraho ibimera bishobora bitera allergie - biragoye cyane kubona ihinduka rya gene ritera gene.intungamubiri nshya. "Kugirango uzamure imirire nyayo, ugomba gusubira inyuma ugatekereza, iki gikoresho cyagira akamaro ki?"Napier ati.
Mugihe ibimera bimwe na bimwe bisanzwe bitanga vitamine D, mubisanzwe nyuma bihinduka imiti igenga imikurire yibihingwa. Gufunga inzira yo guhinduka biganisha ku kwegeranya kwa vitamine D ibanziriza, ariko kandi no gukura kw'ibimera. ”Iki ni ikintu cyingenzi cyane. niba ushaka gukora ibihingwa bitanga umusaruro mwinshi, ”ibi bikaba byavuzwe na Cathie Martin, inzobere mu binyabuzima mu kigo cya John Innes kiri i Norwich, mu Bwongereza.
Ariko nighthades nayo ifite inzira ibangikanye na biohimiki ihindura protitamine D3 mukwirinda.Martin na bagenzi be babikoresheje ibihingwa bya injeniyeri bitanga vitamine D3: Basanze gufunga inzira byatumye habaho kwirundanya.vitamine D.preursors bitabangamiye imikurire yikimera muri laboratoire.
Dominique Van Der Straeten, inzobere mu binyabuzima muri kaminuza ya Ghent yo mu Bubiligi, yavuze ko abashakashatsi bagomba kumenya niba guhagarika umusaruro w’ibikoresho byo kwirwanaho iyo bihinzwe hanze ya laboratoire bigira ingaruka ku bushobozi bw’inyanya kugira ngo bahangane n’ibidukikije.
Martin na bagenzi be barateganya kwiga ibi kandi bamaze kubona uruhushya rwo guhinga inyanya zahinduwe na gene mu murima.Ikipe kandi yashakaga gupima ingaruka ziterwa na UV hanze yo guhindura vitamine D3 na vitamine D3 mumababi yimbuto n'imbuto. . ”Mu Bwongereza, byenda kurimbuka.” Martin asetsa avuga ku bihe by'imvura izwi cyane muri iki gihugu. Yavuze ko ubwo yavuganaga n’umufatanyabikorwa mu Butaliyani kugira ngo amubaze niba ashobora gukora ubushakashatsi ku zuba ryinshi, asubiza ko bizatwara hafi imyaka ibiri kugirango ubone ibyemezo byemewe.
Niba inyanya zikora neza mubushakashatsi bwumurima, zirashobora guhuza urutonde ruto rwibihingwa bikungahaye ku ntungamubiri ziboneka ku baguzi.Ariko Napier iraburira ko umuhanda ujya ku isoko ari muremure kandi wuzuyemo ibibazo bijyanye n'umutungo bwite mu by'ubwenge, ibisabwa n'amategeko ndetse n'ibibazo bya logistique.Golden Umuceri - verisiyo yubuhinzi itanga vitamine A ibanziriza - byatwaye imyaka mirongo yo kuva ku ntebe ya laboratoire ikajya mu mirima, mbere yuko yemererwa guhinga muri Filipine umwaka ushize.
Laboratoire ya Van Der Straeten irimo gukura ibihingwa byahinduwe mu buryo bwa genoside bitanga urugero rwinshi rwintungamubiri zitandukanye, harimo folate, vitamine A na vitamine B2.Ariko yihutira kwerekana ko iki gihingwa gikomeye gishobora gukemura ikibazo cyimirire mibi. "Ni kimwe gusa muri byo inzira dushobora gufasha abantu. "Ati:" Biragaragara ko bizafata ingamba zitandukanye. "
Igihe cyo kohereza: Gicurasi-25-2022