Canada: Vakadzi vane pamuviri, vaiva nenhoroondo yepenicilil allergies vakakwanisa kubudirira kupedza kunwa zvakanangaamoxicillinmatambudziko pasina kudiwa kwekuongororwa kweganda, inodaro imwe nyaya yakabudiswa mukatiIyo Journal yeAllergy uye Clinical Immunology: Mukuita.
Muvanhu vakasiyana-siyana varwere, penicillin allergy de-labeling yakawanikwa yakachengeteka uye yakabudirira muvanhu vane njodzi shoma.Kuongororwa kunoratidza kuti vanhu vanopfuura makumi mapfumbamwe kubva muzana havana alergic pakutanga.Pasinei nechokwadi chokuti kubata pamuviri hakuwedzere ngozi yepenicillin allergy, vakadzi vane pamuviri vanowanzosiiwa kubva pakutsvakurudza kwakawanda.Chidzidzo ichi chakaitwa naRaymond Mak nechikwata pamusoro pekuchengetedzwa kweAmoxicillinmuvakadzi vane pamuviri.
Pakati paChikunguru 2019 naGunyana 2021, varapi paBC Women's Hospital uye Health Center vakapa matambudziko emuromo akananga kuvakadzi mazana maviri nevanomwe vane pamuviri vari pakati pemakore makumi maviri nemasere kusvika makumi matatu nematanhatu ekuberekwa.Nekuti madzimai aya vese vaive nePEN-FAST mamaki 0, yakaratidza, point-ye-kutarisira penicillin allergy yezvokurapa inofungidzira mukana wekuongororwa kwakanaka kweganda, vese vakatongerwa njodzi yakaderera zvakanyanya.Madzimai aya akacherechedzwa kweawa imwe chete mushure mekutora 500 mg yeamoxicillinnemuromo.Vanachiremba vakatora zviratidzo zvavo zvakakosha pakutanga, maminetsi gumi nemashanu gare gare, uye awa mushure.Varwere vasina kuratidza zviratidzo zveIgE-mediated mhinduro vakadzingwa nemirairo yekubata kiriniki kana vaine hanya nekunonoka kuita.
Izvo zvakakosha zvakawanikwa pachidzidzo ichi zvaive zvinotevera:
1. Pakanga pasina pakarepo kana kunonoka hypersensitivity mu203 yevanhu ava.
2. Varwere vana vakasara (1.93%) vaiva nebhenen maculopapular rashes, iyo yakabatwa ne betamethasone valerate 0.1% mafuta uye antihistamines.
3. Chiyero che 1.93% chekupindura chakafananidzwa nechekare chakataurwa 1.99% muhuwandu hwevanhu vasina pamuviri uye 2.5% muhuwandu hwepamuviri.
4. Pakanga pasina vanhu vaida epinephrine kana kuti vakatambura anaphylaxis, uye hapana akapinzwa muchipatara semugumisiro wekuedzwa.
Mukupedzisa, maererano nevatsvakurudzi, kuderedza kudiwa kwekuongororwa kweganda repenicillin kunoderedza mari yeagent, nguva yekiriniki, uye kukosha kwekushanyira subspecialist, izvo zvose zvaizowedzera kutarisirwa kwevarwere panguva yekusununguka uye kusununguka.Kuti uwane humbowo hwakasimba, kumwe kuongorora kwakakura kunodiwa.
ref:Mak, R., Zhang, BY, Paquette, V., Erdle, SC, Van Schalkwyk, JE, Wong, T., Watt, M., & Elwood, C. (2022).Kuchengeteka kweYakananga Oral Dambudziko kune Amoxicillin muVarwere Vane Pamuviri paCanada Tertiary Hospital.MuChinyorwa cheAllergy uye Clinical Immunology: Mukuita.Elsevier BV.
Nguva yekutumira: Kubvumbi-25-2022