Phuputso ea likhoto e fana ka maikutlo a hore ho nkavithamine Ce ka thusa ho thibela ho senyeha ha mesifa, phello e tloaelehileng ea moriana oa chemotherapy doxorubicin.Le hoja lithuto tsa bongaka li hlokahala ho fumana polokeho le katleho ea ho noa vithamine C nakong ea phekolo ea doxorubicin, liphuputso li fana ka maikutlo a hore vithamine C e ka fana ka monyetla oa ho fokotsa litla-morao tse fokolisang ka ho fetisisa tsa moriana.
Liphuputso tsa rona li fana ka maikutlo a hore vithamine C e ka ba phekolo e ka thusang ho phekola lefu la mesifa ea mokokotlo ka mor'a phekolo ea doxorubicin, kahoo e ntlafatsa bokhoni ba bophelo le boleng ba bophelo le ho fokotsa lefu. "
Antonio Viana do Nascimento Filho, M.Sc., Universidad Nova de Julio (UNINOVE), Brazil, sengoli sa pele sa thuto, o tla hlahisa liphuputso kopanong ea selemo le selemo ea American Physiological Society nakong ea kopano ea 2022 Experimental Biology (EB) Philadelphia, April 2-5.
Doxorubicin ke sethethefatsi sa anthracycline chemotherapy seo hangata se sebelisoang le litlhare tse ling tsa chemotherapy ho phekola mofetše oa matsoele, mofetše oa senya, lymphoma, leukemia le mefuta e meng e mengata ea mofetše.Leha e le setlhare se thibelang mofetše, doxorubicin e ka baka mathata a tebileng a pelo le ho senyeha ha mesifa, ka litlamorao tsa nako e telele ho matla a 'mele a baphonyohi le boleng ba bophelo ba bona.
Litla-morao tsena ho nahanoa hore li bakoa ke tlhahiso e feteletseng ea lintho tse sebetsang ka oksijene kapa "li-radicals tsa mahala" 'meleng.Vithamine Cke antioxidant ea tlhaho e ka thusang ho fokotsa khatello ea oxidative, mofuta oa tšenyo e bakoang ke li-radicals tsa mahala.
Phuputsong e fetileng le Univesithi ea Manitoba e Canada, sehlopha se fumane hore vithamine C e ntlafalitse matšoao a bophelo bo botle ba pelo le ho phela ho likhoto tse fanoeng doxorubicin, haholo-holo ka ho fokotsa khatello ea oxidative le ho ruruha.Phuputsong e ncha, ba ile ba hlahloba hore na vithamine C e ka boela ea thusa ho thibela liphello tse mpe tsa doxorubicin mesifa ea masapo.
Bafuputsi ba ile ba bapisa mesifa ea masapo le matšoao a khatello ea oxidative ka lihlopha tse 'nè tsa likhoto, e' ngoe le e 'ngoe ea 8 ho liphoofolo tsa 10.Sehlopha se seng se ile sa nka bobelivithamine Cle doxorubicin, sehlopha sa bobeli se nkile vithamine C feela, sehlopha sa boraro se nkile doxorubicin feela, 'me sehlopha sa bone ha sea ka sa nka leha e le efe.Litoeba tse fuoeng vithamine C le doxorubicin li bontšitse bopaki ba ho fokotseha ha khatello ea oxidative le mesifa e betere ha e bapisoa le litoeba tse fuoeng doxorubicin empa eseng vithamine C.
"Hoa thabisa hore phekolo ea prophylactic le concomitant le vithamine C e fanoeng beke e le 'ngoe pele ho doxorubicin le libeke tse peli ka mor'a hore doxorubicin e lekane ho fokotsa litla-morao tsa moriana ona mesifa ea masapo, kahoo e fokotsa phello e ntle haholo ho mesifa ea masapo.Ho ithuta ka bophelo bo botle ba liphoofolo,” ho bolela Nascimento Filho.” Mosebetsi oa rōna o bontša hore phekolo ea vithamine C e kokobetsa ho lahleheloa ke mesifa ’me e ntlafatsa matšoao a mangata a ho se leka-lekane ha likhoto tse amohetseng doxorubicin.”
Bo-ramahlale ba hlokometse hore lipatlisiso tse ling, ho kenyeletsoa liteko tsa kliniki tse sa reroang, lia hlokahala ho netefatsa hore na ho noa vithamine C nakong ea kalafo ea doxorubicin hoa thusa ho bakuli ba batho le ho fumana tekanyo le nako e nepahetseng.Lipatlisiso tse fetileng li bontša hore vithamine C e ka kena-kenana le liphello tsa meriana ea chemotherapy, kahoo bakuli ha ba eletsoa ho noa li-supplement tsa vithamine C nakong ea phekolo ea kankere ntle le haeba ba laetsoe ke ngaka ea bona.
Nako ea poso: Apr-26-2022