Ukungena kuJAMA kunye neeJenali zooVimba,umfuniselo we-morden kunye noogqirha abangamadoda be-15,000 abakhethiweyo babonisa ukuba ukusetyenziswa kwexesha elide le-multivitamin kubomi bemihla ngemihla ngaphezu kweshumi leminyaka yonyango kunokunciphisa kakhulu amathuba okufumana umhlaza.
“Iivithamini ezininzizezona zixhaphakileyo izongezo zokutya, ezithathwa rhoqo ubuncinane esinye kwisithathu sabadala base-US.Indima yemveli ye-multivitamin yemihla ngemihla kukuthintela ukunqongophala kwezondlo.Ukudityaniswa kweevithamini eziyimfuneko kunye neeminerali eziqulethwe kwii-multivitamins zinokubonisa iipatheni zokutya ezinempilo ezifana nokutya kweziqhamo kunye nemifuno, eziye zayanyaniswa ngokuthozama nangokuchaseneyo nomngcipheko womhlaza kwezinye, kodwa hayi zonke, izifundo ze-epidemiologic.Izifundo zokujonga ukusetyenziswa kwexesha elide le-multivitamin kunye namanqaku okuphela komhlaza ayengahambelani.Ukuza kuthi ga ngoku, izilingo ezinkulu ezivavanya idosi enye okanye encinci yedosi ephezulu yeevithamini kunye neeminerali zomhlaza zifumene ukusilela, ”utshilo kulwazi olungasemva kwijenali.“Ngaphandle kokunqongophala kwedatha yolingo oluchanekileyo malunga noncedo lweiivithamini ezininziekuthinteleni izifo ezinganyangekiyo, kuquka umhlaza, amadoda namabhinqa amaninzi azithatha kanye ngenxa yesi sizathu.”
J. Michael Gaziano, MD, MPH, waseBrigham kunye neSibhedlele sabaseTyhini kunye neSikole sezoNyango saseHarvard, eBoston, (kunye noMhleli oNcedisayo,JAMA), kunye noogxa bahlalutya idatha evela kwi-Physicians 'Health Study (PHS) II, kuphela imilinganiselo emikhulu, i-randomized, i-double-blind, i-placebo-controlled controlled test imiphumo yexesha elide ye-multivitamin eqhelekileyo ekuthinteleni isifo esingapheliyo.Olu vavanyo lwamema i-14,641 yamadoda ogqirha baseMelika abangaphezulu kweminyaka engama-50, kubandakanya amadoda ali-1,312 anomhlaza kwimbali yawo yezonyango.Baye babhaliswa kwisifundo se-multivitamin esaqala kwi-1997 ngonyango kunye nokulandelwa kwe-Juni 1, 2011. Abathathi-nxaxheba bafumana i-multivitamin yemihla ngemihla okanye i-placebo efanayo.Esona siphumo silinganisiweyo sophononongo yaba ngumhlaza opheleleyo (ngaphandle komhlaza wolusu we-nonmelanoma), kunye ne-prostate, i-colorectal, kunye nezinye iindawo zomhlaza ezikhethekileyo phakathi kweendawo zokugqibela zesibini.
Abathathi-nxaxheba be-PHS II balandelwa umyinge weminyaka eyi-11.2.Ngexesha lonyango lwe-multivitamin, bekukho iimeko ze-2,669 eziqinisekisiweyo zomhlaza, kubandakanywa iimeko ze-1,373 zomhlaza we-prostate kunye neemeko ze-210 zomhlaza we-colorectal, kunye namadoda athile afumana iziganeko ezininzi.Isamba se-2,757 (i-18.8 ekhulwini) yamadoda yafa ngexesha lokulandelwa, kuquka i-859 (i-5.9 ekhulwini) ngenxa yomhlaza.Uhlalutyo lwedatha lubonise ukuba amadoda athatha i-multivitamin ayenokunciphisa i-8 ekhulwini kwisiganeko somhlaza.Amadoda athatha i-multivitamin ayenokuncipha okufanayo kwi-epithelial cell cell cancer.Malunga nesiqingatha sazo zonke iziganeko zomhlaza ibingumhlaza wedlala lobudoda, uninzi lwazo bezikwinqanaba lakwangoko.Abaphandi abafumananga siphumo se-multivitamin kumhlaza we-prostate, ngelixa i-multivitamin yanciphisa kakhulu umngcipheko womhlaza opheleleyo ngaphandle komhlaza we-prostate.Akukho nciphiso lubalulekileyo ngokweenkcukacha zomhlaza kwindawo ethile, kubandakanya i-colorectal, imiphunga, kunye nomhlaza wesinyi, okanye ekufeni komhlaza.
Ukusetyenziswa kwe-multivitamin yemihla ngemihla kukwanxulunyaniswa nokuncitshiswa komhlaza uwonke phakathi kwamadoda ayi-1,312 anembali esisiseko yomhlaza, kodwa esi siphumo asizange sahluke kakhulu koko kubonwe phakathi kwamadoda angama-13,329 ekuqaleni ngaphandle komhlaza.
Abaphandi baqaphela ukuba amazinga omhlaza ewonke kulingo lwabo anokuthi aphenjelelwe kukonyuka kovavanyo lwe-prostate-specific antigen (PSA) kunye noxilongo olulandelayo lomhlaza wedlala lesinyi ngexesha lokulandelelwa kwe-PHS II ukuqala ngasekupheleni kweminyaka yoo-1990.Malunga nesiqingatha sazo zonke izifo zomhlaza eziqinisekisiweyo kwi-PHS II ibingumhlaza wedlala lesinyi, uninzi lwazo bezikwinqanaba langaphambili, umhlaza wedlala lobudoda okumgangatho ophantsi onamazinga aphezulu okusinda.Ukwehliswa okubalulekileyo komhlaza we-prostate uphela ubonisa ukuba ukusetyenziswa kwe-multivitamin mihla le kunokuba nenzuzo enkulu kuxilongo olufanelekileyo lomhlaza.
Ababhali bongeza ukuba nangona uninzi lweevithamini kunye neeminerali eziqulethwe kuphononongo lwe-PHS II ye-multivitamin ziye zachaza iindima ze-chemopreventive, kunzima ukuchonga ngokuqinisekileyo nayiphi na indlela enye yesiphumo apho umntu okanye amacandelo amaninzi e-multivitamin yabo evavanyiweyo inokunciphisa umngcipheko womhlaza."Ukunciphisa umngcipheko womhlaza kwi-PHS II ithi indibaniselwano ebanzi yeevithamini ezinedosi ephantsi kunye neeminerali eziqulethwe kwi-PHS II multivitamin, kunokuba kugxininiswe kwidosi ephezulu yeevithamini kunye nezilingo zeeminerali ezivavanyiweyo ngaphambili, kunokuba yeyona nto iphambili ekuthinteleni umhlaza. .…
"Nangona isizathu esona sizathu sokuthatha i-multivitamins kukuthintela ukunqongophala kwezondlo, ezi nkcukacha zibonelela ngenkxaso yokusetyenziswa kwe-multivitamin supplements ekukhuseleni umhlaza kumadoda aneminyaka ephakathi kunye nabadala," abaphandi baphetha.
Ixesha lokuposa: Apr-19-2022