Iithebhu ze-Artemether+ lumefantrine

Inkcazelo emfutshane:

· Ixabiso & neNtelekelelo yexabiso: FOB Shanghai: Thetha ngoMntu · Isibuko sokuThumela: eShanghai, eTianjin, Guangzhou, Qingdao · MOQ(20mg+120mg):50000iibhokisi · ImiGaqo yeNtlawulo: T/T, L/C Iinkcukacha zeMveliso Composit...

  • : Iquka umlinganiselo omiselweyo we-1: 6 iinxalenye ze-artemether kunye ne-lumefantrine ngokulandelelanayo.Isayithi yesenzo sokulwa ne-parasitic yamacandelo omabini yi-vacuole yokutya ye-malaria parasite, apho kucingelwa ukuba iphazamise ukuguqulwa kwe-haem, i-intermediate eyityhefu. iveliswe ngexesha lokuqhekeka kwe-heamoglobin, kwi-haenozoin engeyiyo ityhefu, i-malaria pigment.I-Lumefantrine kucingelwa ukuba iphazamisana nenkqubo ye-polymerisation ngelixa i-artemether ivelisa i-metabolites esebenzayo ngenxa yentsebenziswano phakathi kwe-peroxide nucleic acid yayo, kunye ne-protein synthesis ngaphakathi kwe-malaria parasite.Idatha evela kwi-vitro kunye nezifundo ze-vivo zibonisa ukuba ayizange ibangele ukuxhathisa.I-antimalarial cativity yendibaniselwano yelumefantrine kunye ne-artemether ekuyo inkulu kunolo lwe-erther substance iyodwa.
  • Iinkcukacha zeMveliso

    Iithegi zeMveliso

    • ·Ixabiso kunye neNtelekelelo:FOB Shanghai: Xoxa ngoMntu
    • ·Indawo yokuthumela ngenqanawa:eShanghai,eTianjin,eGuangzhou,Qingdao 
    • ·MOQ(20mg+120mg):50000ibhokisis
    • ·Immimiselo yokuhlawula:T/T, L/C

    Iinkcukacha zemveliso

    Ukuqamba
    Ithebhulethi nganye iquletheArtemether20mg,Lumefantrine120mg.

    Isalathiso
    I-Itis indibaniselwano ye-artemether kunye ne-lumfentrie, esebenza njenge-schozincie yegazi Ilungiselelwe unyango lwabantu abadala kunye nabantwana abane-acute, i-ifctions enzima ngenxa ye-Plasmodium faliparum okanye i-ifentio edibeneyo kuquka i-P. Faciparium kunye neentlobo ezivela kwiindawo ezininzi ezichasene neziyobisi.
    Kucetyiswa ukuba isetyenziswe njengonyango olungxamisekileyo olulindileyo kwiindawo apho iprasite ixhathisa kwezinye iziyobisi.

    Contraindications

    Ayivumelekanga kwi:
    -I-Hypersensitivity kwi-artemether, ilumefantrine okanye nakweyiphi na into encedisayo
    -Izigulane ezinemalariya ezinzima ngokwenkcazo ye-WHO.
    -Ikota yokuqala yokukhulelwa.
    -Izigulane ezinembali yosapho yokuzalwa kwexesha le-QTc okanye ukufa ngokukhawuleza okanye nayiphi na enye imeko yeklinikhi eyaziwayo yokwandisa ixesha le-QTc njengezigulane ezine-historv ye-symptomatic arrhythmias ye-cardiac, ene-bradycardia ehambelana neklinikhi okanye enesifo esibi senhliziyo.
    -Izigulana ezinokuphazamiseka okwaziwayo kokungalingani kwe-electrolyte umz. hypokalemia okanye hypomagnesaemia.
    -Izigulane ezithatha nayiphi na iziyobisi, ezixutywe yi-enzyme ye-cytochrome CYP206 (umzekelo, i-Hecainde, i-metaprolol, imipramine, i-amitriptyline, i-clomipramine)
    -Izigulane ezithatha iziyobisi ezaziwa ngokwandisa ixesha le-QTc njenge-antarrhythics yeeklasi ze-la kunye ne-II, i-neuroleptics, kunye ne-antidepressive agents.

    Imiphumo emibi

    Ezi ziphumo zilandelayo zibi ziye zaxelwa;isiyezi kunye nokudinwa, izigulana eziwufumanayo akufanele ziqhube okanye zisebenzise umatshini, i-anorexia, isicaphucaphu, ukugabha, iintlungu zesisu, ukubetha kwentliziyo, i-myalgia, ukuphazamiseka kokulala, i-arthralgia, intloko ebuhlungu kunye nerhashalala.

    Kubantwana nakubantu abadala abanyangwa ngolu hlanganiso, ukuphindaphindwa kunye neqondo lokolulwa kwe-QTc bekusezantsi xa kuthelekiswa nezinye ii-antimalarials.Uphononongo alubonisi zimpawu zetyhefu ye-cardio.

    Umthamo kunye noLawulo
    Kulawulo lomlomo
    kufuneka ithathwe ngokutya okunamafutha aphezulu okanye iziselo ezifana nobisi.Izigulana kufuneka zikhuthazwe ukuba ziphinde ziqalise ukutya okuqhelekileyo ngokukhawuleza nje ukuba ukutya kunokunyamezela kuba oku kuphucula ukufunxa kwe-artemether kunye nelumefantrine.Ngomcimbi weukuhlanza ngaphakathi kweyure ye-1 yolawulo, i-dose yokuphinda kufuneka ithathwe.
    Abantu abadala: Icwecwe eli-1 lokuqala kunye necwecwe eli-1 kufuneka liphindwe emva kweeyure ezi-8 kwaye emva koko ithebhulethi enye kufuneka ithathwe amaxesha ama-2 yonke imihla kwiintsuku ezi-2 ezizayo (Iipilisi ezi-6 zizonke).

    Ukugcinwa kunye nexesha eliphelelwe lixesha
    Gcinangaphantsi kwe-30.indawo eyomileyo.

    GCINA AKUFIMELEKANGA ABANTWANA.

    3 iminyaka
    Ukupakisha
    24's/Iblister/ibhokisi

    Ukugxila
    20mg+120mg


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