Umthombo: isikhathi sokuhlanganisa imithi yomhlaba wonke: Septhemba 18, 2021
Iningi leziguli ezine-pneumonia ye-coronavirus zigula ngokusesilinganisweni futhi ekuqaleni azikudingi ukwesekwa kwezitho ku-ICU.I-Novel coronavirus pneumonia yasetshenziswa ocwaningweni lwe-N Engl J Med ngo-Agasti 2021. Abacwaningi baseCanada, e-United States naseBrazil bashicilela izincwadi zasendulo zaseShayina zokusesha umphumela wokwelashwa kwe-anticoagulant we-heparin anticoagulation therapy ezigulini ezingezona ezinzima ezine-pneumonia entsha yomqhele.
Isendlalelo: inoveli coronavirus pneumonia ihlotshaniswa nokufa kanye nezinkinga ngenxa ye-thrombosis nokuvuvukala.Abacwaningi bacabanga ukuthi inyumoniya entsha ye-coronavirus ingathuthukisa umphumela weziguli ezingabalulekile ezibhedlela ezinenyumoniya entsha yomqhele.
Izindlela: inoveli coronavirus inyumoniya (ukwesekwa okungezona izitho), echazwa njengezinga lokunakekelwa okungabalulekile, yabelwa ngezikhathi ezithile ezincazelweni ezisebenzayo ezi-2: i-heparin anticoagulation noma i-thrombus prophylaxis evamile kulesi siteji esivulekile, esiguquguqukayo, esiningi, esilawulwayo.Umphumela oyinhloko wawuyinani lezinsuku ngaphandle kokusekelwa kwezitho, ezihlolwe isikali esilandelanayo esihlanganisa ukufa kwasesibhedlela (amaphuzu - 1) kanye nenani lezinsuku zeziguli ezisinde ukuze ziphume ngaphandle kokusekelwa kwenhliziyo nemithambo yegazi noma isitho sokuphefumula kuze kube usuku lwama-21. Yonke imiphumela yesiguli yahlolwa kusetshenziswa amamodeli ezibalo e-Bayesian futhi ngokusekelwe kumazinga ayisisekelo e-D-dimer.
Imiphumela: lapho umthamo wokwelapha we-anticoagulation uhlangabezana nenqubo yokuphakama esethiwe, ukuhlolwa kuyekwa.Phakathi kweziguli ezingama-2219 ekuhlaziyeni kokugcina, amathuba okwelapha umthamo we-anticoagulation okwandisa inani lezinsuku ngaphandle kokusekelwa kwesitho uma kuqhathaniswa ne-thromboprophylaxis evamile ayengama-98.6% (okulungisiwe noma, 1.27; 95% CI, 1.03 ~ 1.58).Umehluko ophelele phakathi kwamaqembu ekulungisweni kokusinda ukuze kukhishwe ngaphandle kokusekelwa kwesitho kubonise ukuthi umthamo wokwelapha we-anticoagulation wawungcono, futhi umehluko phakathi kwamaqembu amabili wawungu-4.0% (0.5 ~ 7.2).Amathuba okugcina okuphakama kwe-anticoagulation yomthamo wokwelapha ngaphezu kwe-thromboprophylaxis evamile ayengu-97.3%, 92.9% kanye nama-97.3% kuqoqo eliphezulu le-D-dimer, iqoqo eliphansi le-D-dimer kanye neqembu le-D-dimer elingaziwa, ngokulandelana.Ukopha okukhulu kwenzeka ku-1.9% no-0.9% weziguli kumthamo wokwelashwa weqembu le-anticoagulation kanye neqembu lokuvimbela i-thrombosis, ngokulandelana.
Isiphetho: isu elinoveli le-coronavirus pneumonia lingakhuphula amathuba okusinda kanye nokuphuma kwegazi futhi linciphise ukusetshenziswa kokusekelwa kwenhliziyo nemithambo yegazi noma ukuphefumula ezigulini ezinenyumoniya entsha engenamandla.
Isikhathi sokuthumela: Sep-18-2021